Factor V Leiden Thrombophilia

DC 7199-7121Hematologic/Lymphatic38 CFR 4.117, DC 7199-7121

A genetic clotting disorder caused by a mutation in the Factor V gene that makes your blood more likely to form clots, especially in deep veins (DVT) and lungs (PE). Because there is no specific diagnostic code, the VA rates Factor V Leiden by analogy to DC 7121 (post-phlebitic syndrome). The rating depends on the severity of clotting complications and their residual effects.

How the VA rates this condition

The VA rates this condition based on the type, severity, and frequency of your symptoms. The examiner will evaluate your specific symptoms and how they affect your daily life and ability to work.

Diagnostic code

DC 7199-7121

Rating range

0% – 100%

Rating levels

Rating criteria are defined in 38 CFR 4.117, DC 7199-7121. This guide presents a plain-language summary and is not a substitute for the full regulatory text. Always consult a VSO or VA-accredited attorney for case-specific advice.

Rating Levels

You have massive board-like swelling with constant pain at rest, or you have life-threatening complications such as severe pulmonary hypertension from recurrent pulmonary emboli.

What the VA looks for

Massive board-like edema
Constant pain at rest
Severe pulmonary hypertension
Right heart failure from recurrent PE
Inability to perform daily activities

Common Pitfalls

⚠Not understanding that Factor V Leiden itself can be service-connected if a clotting event first manifested during military service — even though the mutation is genetic, the aggravation or first manifestation during service can establish service connection.
⚠Failing to file separate claims for each affected extremity — DVT residuals are rated per leg, so bilateral clots should result in two separate ratings.
⚠Not documenting the impact of lifelong anticoagulation therapy including bleeding risks, regular INR monitoring, medication interactions, and activity restrictions.
⚠Overlooking secondary conditions caused by recurrent PE such as pulmonary hypertension, right heart strain, and chronic shortness of breath that deserve separate ratings.

Related DBQ Forms

DBQ Hematologic and Lymphatic Conditions
DBQ Artery and Vein Conditions

View evidence checklist →See secondary conditions →

Condition Rating Guides

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Factor V Leiden Thrombophilia

How the VA rates this condition

The VA rates this condition based on the type, severity, and frequency of your symptoms. The examiner will evaluate your specific symptoms and how they affect your daily life and ability to work.

Diagnostic code

DC 7199-7121

Rating range

0% – 100%

Rating levels

Rating Levels

You have massive board-like swelling with constant pain at rest, or you have life-threatening complications such as severe pulmonary hypertension from recurrent pulmonary emboli.

What the VA looks for

Massive board-like edema
Constant pain at rest
Severe pulmonary hypertension
Right heart failure from recurrent PE
Inability to perform daily activities

Common Pitfalls

⚠Not understanding that Factor V Leiden itself can be service-connected if a clotting event first manifested during military service — even though the mutation is genetic, the aggravation or first manifestation during service can establish service connection.

⚠Failing to file separate claims for each affected extremity — DVT residuals are rated per leg, so bilateral clots should result in two separate ratings.

⚠Not documenting the impact of lifelong anticoagulation therapy including bleeding risks, regular INR monitoring, medication interactions, and activity restrictions.

⚠Overlooking secondary conditions caused by recurrent PE such as pulmonary hypertension, right heart strain, and chronic shortness of breath that deserve separate ratings.