Evidence Checklist: Hyperaldosteronism (Conn's Syndrome)

Endocrinology evaluation and treatment recordsCritical

Records documenting mineralocorticoid receptor antagonist therapy (spironolactone/eplerenone) or adrenalectomy and blood pressure control.

Nexus opinion linking hyperaldosteronism to service or toxic exposureCritical

Medical opinion connecting primary aldosteronism to military service or toxic chemical exposure.

Plasma aldosterone-to-renin ratio (ARR), confirmatory suppression testCritical

Screening and confirmatory laboratory results documenting autonomous aldosterone excess (elevated ARR, non-suppressible aldosterone).

Adrenal CT and adrenal vein sampling resultsCritical

Imaging to identify adrenal adenoma and adrenal vein sampling to lateralize aldosterone production for surgical planning.

Buddy statement from spouse, family, or fellow service member

A written statement from someone who can describe observable symptoms and how your condition affects daily life.

Personal statement describing symptoms and functional impact

Your own written account of how this condition affects your daily activities, work, and relationships. Describe your worst days.

Service treatment records (STRs)Critical

Military medical records showing in-service treatment, complaints, or injuries related to this condition.