Evidence Checklist: Multiple Sclerosis

MRI brain and spinal cord showing demyelinating plaquesCritical

MRI documenting T2/FLAIR hyperintense lesions in white matter, periventricular, juxtacortical, infratentorial, or spinal cord locations consistent with MS (McDonald criteria).

Lumbar puncture CSF analysis (oligoclonal bands, IgG index)

CSF results showing oligoclonal bands or elevated IgG index, which support the MS diagnosis under McDonald criteria.

Nexus opinion linking MS to service ("at least as likely as not")Critical

Medical opinion connecting your MS to military service. MS is a presumptive condition for veterans with active service, and nexus may also be established through documented onset during service.

Neurologist evaluation documenting EDSS and functional statusCritical

A neurologist's evaluation including the Expanded Disability Status Scale (EDSS) score or equivalent functional assessment documenting the current level of neurological impairment.

Evoked potential studies (VEP, SSEP, BAEP)

Electrophysiological testing showing slowed conduction in visual, somatosensory, or brainstem pathways consistent with demyelination.

Treatment records (disease-modifying therapy, rehabilitation)

Records of disease-modifying treatments (interferons, natalizumab, ocrelizumab), relapse history, hospitalizations, and rehabilitation.

Buddy statement from spouse, family, or fellow service member

A written statement from someone who can describe observable symptoms and how your condition affects daily life.

Personal statement describing symptoms and functional impact

Your own written account of how this condition affects your daily activities, work, and relationships. Describe your worst days.

Completed DBQ Multiple SclerosisCritical

VA standardized form for MS capturing neurological deficits, EDSS, incapacitation episodes, and functional limitations.

Service treatment records (STRs)Critical

Military medical records showing in-service treatment, complaints, or injuries related to this condition.